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Driving science and ethics in gut–brain–metabolic health.

Driving science and ethics in gut–brain–metabolic health.Driving science and ethics in gut–brain–metabolic health.Driving science and ethics in gut–brain–metabolic health.

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  • Home
  • Our Story
  • PROTEIN SYSTEMS
    • Protein Timing Explained
    • Protein Timing (Under 40)
    • Protein Timing (Over 40)
    • Preventing Muscle Loss
    • Smart Protein Choice
    • The Clean Protein Myth
    • Precision Dosing
    • The Flavor Blind Spot
    • The Sweetener Problem
  • Product Guidance
    • Product Use & Dosing
    • Batch Quality & Reports
    • FAQs
  • MICROBIOME NETWORKS
    • BGM System
    • The Intestinal Barrier
    • Leaky Gut and Disease
    • Healing the Barrier
    • The Gut–Brain–Stress Loop
  • Neuroscience
    • Brain Predicts the World
    • Prediction Gone Wrong
    • Training the Machine
  • Metabolic Sciences
    • Metabolic Strategies
    • KetoTherapy and the Brain
    • The Fermentation Fix
  • More
    • Home
    • Our Story
    • PROTEIN SYSTEMS
      • Protein Timing Explained
      • Protein Timing (Under 40)
      • Protein Timing (Over 40)
      • Preventing Muscle Loss
      • Smart Protein Choice
      • The Clean Protein Myth
      • Precision Dosing
      • The Flavor Blind Spot
      • The Sweetener Problem
    • Product Guidance
      • Product Use & Dosing
      • Batch Quality & Reports
      • FAQs
    • MICROBIOME NETWORKS
      • BGM System
      • The Intestinal Barrier
      • Leaky Gut and Disease
      • Healing the Barrier
      • The Gut–Brain–Stress Loop
    • Neuroscience
      • Brain Predicts the World
      • Prediction Gone Wrong
      • Training the Machine
    • Metabolic Sciences
      • Metabolic Strategies
      • KetoTherapy and the Brain
      • The Fermentation Fix

Built by Family. Backed by Science™

Driving science and ethics in gut–brain–metabolic health.

Driving science and ethics in gut–brain–metabolic health.Driving science and ethics in gut–brain–metabolic health.Driving science and ethics in gut–brain–metabolic health.
  • Home
  • Our Story
  • PROTEIN SYSTEMS
    • Protein Timing Explained
    • Protein Timing (Under 40)
    • Protein Timing (Over 40)
    • Preventing Muscle Loss
    • Smart Protein Choice
    • The Clean Protein Myth
    • Precision Dosing
    • The Flavor Blind Spot
    • The Sweetener Problem
  • Product Guidance
    • Product Use & Dosing
    • Batch Quality & Reports
    • FAQs
  • MICROBIOME NETWORKS
    • BGM System
    • The Intestinal Barrier
    • Leaky Gut and Disease
    • Healing the Barrier
    • The Gut–Brain–Stress Loop
  • Neuroscience
    • Brain Predicts the World
    • Prediction Gone Wrong
    • Training the Machine
  • Metabolic Sciences
    • Metabolic Strategies
    • KetoTherapy and the Brain
    • The Fermentation Fix

Important Disclaimer

This tool is for educational purposes only and does not provide medical or dietary advice. Protein needs vary based on individual metabolism, training intensity, overall diet, health status, and medications. Always consult a qualified healthcare provider or registered dietitian before making significant dietary changes, especially if you have medical conditions. 

TLC Precision Dosage™

Before using the calculator, watch this short introduction to understand the science behind TLC Precision Dosage™, and why more protein isn’t always better. Then find your personalized scoop below. Full scientific references are available after the calculator.  👇 Try the TLC Precision Dosage Calculator here: Beta Version.

How This Protein Calculator Works

Your body doesn’t respond to protein endlessly. It responds once a minimum amount and quality is reached in a single meal. This minimum is called the muscle activation threshold, often referred to as the leucine threshold. When a meal reaches this threshold, your muscles “switch on” and begin repairing and building tissue. Eating far more protein in that same sitting does not multiply the activation signal. However, slightly higher protein amounts can support whole-body needs beyond muscle alone. Because of this, protein needs are not just about daily totals. They are also about how much protein you get in one sitting.


How We Personalize Your Results. This calculator considers three key physiological factors:


1. Lean (Reference) Body Weight

We estimate a healthy reference weight from your height using a standard BMI guideline.

This prevents over- or under-estimating protein needs, particularly when body fat is higher or lower than average. It is simply a dosing reference, not a judgment of health. If your BMI exceeds the reference range, calculations use a conservative lean-adjusted weight to avoid overstating protein requirements.


2. Daily Protein Target

Your daily protein needs change with:

  • Age
     
  • Activity level
     
  • Training load
     
  • Illness or frailty
     

As we age, muscle becomes less responsive to protein, a process known as anabolic resistance. This means slightly higher protein quality or dose may be required to achieve the same muscle response seen in younger adults.


Your daily protein range (grams per day) ensures you are supporting:

  • Muscle repair and growth
     
  • Connective tissue and skin turnover
     
  • Gut lining renewal
     
  • Immune function
     
  • Enzyme and hormone production
     
  • Healthy aging physiology
     

3. Per-Meal Muscle Activation Target

Muscle protein synthesis happens meal by meal, not in one large daily total.

Each meal must contain enough high-quality protein to reach your leucine target:

  • Age ≤39: ~2.2 g leucine
     
  • Age 40–59: ~2.5 g leucine
     
  • 60+ active: ~2.8 g leucine
     
  • 60+ sedentary or frail: ~3.0 g leucine
     

Leucine acts as the biological “signal” that switches on muscle building. Once that threshold is reached, muscle activation begins. However, consuming somewhat more protein per meal may help support total tissue needs beyond muscle alone.


Why You See a Scoop Range


Your “Precision Scoop Dose” shows a range for a reason.

  • The lower value meets your leucine (muscle activation) threshold.
     
  • The upper value optimizes total protein intake for whole-body health and aging support.
     

This reflects both:

  • Activation (signal)
     
  • Substrate availability (building material)
     

Why Flavour Matters

Different protein flavours contain slightly different protein concentrations per scoop. Because leucine is proportional to protein content, some flavours may require a slightly larger scoop amount to reach the same muscle activation threshold. The calculator adjusts automatically.


How Protein Powder Fits In


Whole foods should always form the foundation of your diet: Meat, fish, eggs, dairy, legumes, and nuts.
 

Protein powder is a supplement, not a replacement. TLC PureProtein is designed to:

  • Help you consistently reach your per-meal activation target
     
  • Support your daily protein intake
     
  •  Simplify dosing when whole foods aren’t convenient
     

The Big Picture


Think of protein intake in three layers:

  1. Activation — reaching the leucine threshold per meal
     
  2. Optimization — adequate protein per sitting for whole-body support
     
  3. Total sufficiency — meeting your daily grams per kilogram target
     

This calculator brings all three together in one clear plan.

DOWNLOAD THE FULL SCIENTIFIC PDF WITH REFERENCES

© 2025 TLC NeuroMicrobiome Labs Inc.
Educational content only; not intended to diagnose or treat disease. Consult a qualified professional before major dietary changes.

Anabolic Resistance, the Leucine Threshold, and Protein Requirements Across the Adult Lifespan (pdf)Download
Supplementary Table S1. summary for age-specific protein and leucine recommendations (pdf)Download
Net Protein Balance- Why Timing Matters for Young Lifters (pdf)Download
Net Protein Balance- Why Timing Matters Even More for Older Lifters (pdf)Download
The Leucine Threshold- Why Not All Protein Portions Are Created Equal (pdf)Download

Copyright © 2026 The TLC Company - All Rights Reserved.


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