TLC PureProtein 80™ — The Science of Precision Dosing

At TLC PureOrigin™, we believe nutrition should be as precise as medicine. TLC PureProtein 80™ was formulated with a calibrated scoop that delivers the exact protein and leucine dose your body needs to support muscle repair, strength, and healthy aging, nothing more, nothing wasted.

For years, the fitness industry has promoted a simple idea: eat more protein, build more muscle.
But science tells a different story. Muscle responds not to total protein intake but to the amino acid leucine, which activates mTORC1, the master regulator of muscle repair and metabolic renewal. Once the leucine threshold is reached, additional protein offers no further anabolic benefit and simply increases metabolic workload.

When you consume protein, it’s broken down into amino acids. Leucine acts as a biological signal, activating mTORC1 to initiate muscle-protein synthesis (MPS). Once this threshold is met, the muscle enters the “muscle-full” state. Amino acids will remain in circulation, but synthesis no longer increases. Think of it like a dimmer, not a switch: as we age, the signal must shine brighter (more leucine) to achieve the same response.

The TLC Precision Dosing System™ isn’t a generic calculator. Each recommendation is manually derived from the measured protein and leucine content per 100 g of TLC PureProtein 80™ and aligned with clinical dose–response studies defining age-specific leucine thresholds. These values are based on evidence summarized in my article titled (see attached) “Anabolic Resistance, the Leucine Threshold, and Protein Requirements Across the Adult Lifespan,” and in Supplementary Table S1, which compile data from ESPEN (2014), PROT-AGE (2013), Layman (2024), Bauer et al. (2013), Deutz et al. (2014), Moore, Witard et al. (2014), Katsanos et al. (2006), Yang et al. (2012), and Zaromskyte et al. (2021). 

Based on verified protein (75.8 %) and leucine (7.996 %) content of TLC PureProtein 80™

For Adults Under 39 Years
→ 1 scoop (≈ 30 g powder)
≈ 22.7 g protein  |  ≈ 2.4 g leucine
Meets the leucine threshold for optimal repair, recovery, and metabolic efficiency.

For Adults 40–59 Years
→ 1–1.2 scoops (≈ 30–36 g)
≈ 23–27 g protein  |  ≈ 2.4–2.8 g leucine
Addresses early-onset anabolic resistance while maintaining efficiency within the muscle-full range.

For Adults 60+ Years (Sedentary or Minimally Active, Healthy)
→ 1.5 scoops (≈ 45 g)
≈ 34 g protein  |  ≈ 3.0 g leucine
Achieves optimal stimulation for older adults with lower habitual activity.
Active / Regular Exercise: follow the same guideline as adults 40–59 years, or slightly higher if recovery demands increase.

For Frail, Clinical, or Rehabilitation Populations
→ Up to 2 scoops (≈ 60 g)
≈ 45 g protein  |  ≈ 4.8 g leucine
Supports severe anabolic resistance or disuse atrophy where compensatory protein needs are elevated.

Full reference list available in the attached literature review.

Our choice of Whey Protein Concentrate 80 (WPC-80) is intentional. It provides a naturally high leucine content that delivers a rapid plasma rise, efficiently activating mTORC1—the key signal for muscle protein synthesis. This kinetic advantage is especially important for older adults who require a stronger anabolic signal to overcome age-related anabolic resistance. WPC-80 also naturally contains glycomacropeptide (GMP), a bioactive peptide with prebiotic effects, shown to support gut integrity, immune modulation, and metabolic balance (Furlan et al., 2019; Manso et al., 2021).

TLC PureProtein 80™ is non-instantized, containing no lecithin or anti-caking agents.
While most commercial powders use soy or sunflower lecithin to make mixing easier, these emulsifiers can disrupt the gut microbiome and weaken barrier function. By choosing purity over convenience, we protect your gut health, even if that means clumping is normal. Just shake vigorously and enjoy knowing every scoop supports your microbiome, not harms it.

• Add your scoop based on age and activity level (see Precision Dosing Chart):
  • ≤ 39 yr → 1 scoop (≈ 30 g)
  • 40–59 yr → 1–1.2 scoops (≈ 30–36 g)
  • ≥ 60 yr (sedentary/minimally active) → 1.5 scoops (≈ 45 g)
  • ≥ 60 yr (active, post-exercise, or during rehab) → up to 2 scoops (≈ 60 g)
• Add to 6–10 oz (180–300 mL) of cold water or milk.
• Shake vigorously for 25–30 seconds (or blend 20–30 seconds).
• Let rest for 60 seconds to settle naturally before drinking.
• Store in a cool, dry place away from direct sunlight.

TLC PureProtein 80™ is non-instantized and free of lecithin or anti-caking agents to protect your microbiome. Clumping is natural so a few extra shakes are worth it for purity and performance.

• Post-workout: within 1–2 hours of training
• Between meals: mix into yogurt, oats, or smoothies
• Daily use: consistency beats quantity. Steady signals matter most

• Precision dosing maximizes recovery and metabolic efficiency
• Extra protein ≠ extra muscle
• “More” isn’t better — precise is better
• Chronic overconsumption should be clinically monitored

Get personalized, research-based protein guidance without doing any calculations. Just find your age range in the TLC Precision Dosing chart above, match it to your scoop size, and use it consistently to support strength, recovery, and metabolic health.